Dataset for 'Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters'
Published:30 August 2024|Version 1|DOI:10.17632/7my7sszcff.1
Contributors:, , , , , , , , , ,
Description
This dataset contains the raw data supporting all main and supplementary figures used in the manuscript "Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters," published in Journal of Virology (JVI). The data includes measurements of humoral and cellular immune responses in Syrian hamsters following immunization with the nanoparticle recombinant Spike (S) protein-based COVID-19 vaccine (Novavax, Inc.) from different variants. It also includes data comparing the efficacy of the updated monovalent XBB.1.5 variant vaccine to previous COVID-19 vaccines in inducing XBB.1.5 and EG.5.1 neutralizing antibodies and in protecting against a challenge with the EG.5.1 variant of SARS-CoV-2.
Steps to reproduce
Refer to the "Materials and Methods" section of the publication.
Dataset for 'Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters'
Published:17 March 2026|Version 2|DOI:10.17632/7my7sszcff.2
Contributors:, , , , , , , , , ,
Description
This dataset contains the raw data supporting all main and supplementary figures used in the manuscript "Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters," published in Journal of Virology (JVI). The data includes measurements of humoral and cellular immune responses in Syrian hamsters following immunization with the nanoparticle recombinant Spike (S) protein-based COVID-19 vaccine (Novavax, Inc.) from different variants. It also includes data comparing the efficacy of the updated monovalent XBB.1.5 variant vaccine to previous COVID-19 vaccines in inducing XBB.1.5 and EG.5.1 neutralizing antibodies and in protecting against a challenge with the EG.5.1 variant of SARS-CoV-2.
Steps to reproduce
Refer to the "Materials and Methods" section of the publication.
