Performance of Risk Models for Antimicrobial Resistance in Adult Patients with Sepsis
Description
This was a retrospective cohort study (N = 39,893) conducted from January 2016 to October 2021. Adult patients with sepsis at 10 acute-care hospitals in rural and urban areas across Missouri and Illinois were included. Inclusion criteria were blood cultures indicating sepsis, having received 4 days of antibiotic treatment, and having organ dysfunction (vasopressor use, mechanical ventilation, increased creatinine or bilirubin levels, and thrombocytopenia). Analyses were completed in April 2024. There are 11 data files: demographics, diagnoses, diagnoses_for_comorbidities, culture_w_sensitivities, labs, antibiotics, procedures, rooms_wards, vasopressors, vitals, and missing_labs. This study was approved by the Washington University in St. Louis Institutional Review Board (ID# 202109085).
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Steps to reproduce
Adult patients who met the US Centers for Disease Control and Prevention (CDC) adult sepsis event criteria admitted to any of the 10 acute-care BJC hospitals (located across the Greater St Louis region, including urban and rural areas of Missouri and Illinois) between January 2016 and October 2021 were included in the study. Data were directly extracted and timestamped as recorded in the electronic health record (EHR). Refer to the Methods Section and Supplementary File 1 of the manuscript for details. Hospital information is not available due to insufficient de-identification.
Institutions
- Washington University in St. LouisMO, Saint Louis
Categories
Funders
- Foundation for Barnes-Jewish Hospital
Additional Metadata for Digital Commons Data@Becker
| Keywords | Adult, Cefepime, Ceftriaxone, Anti-Bacterial Agents, Retrospective Studies, Prevalence, Drug Resistance, Bacterial, Sepsis, Gram-Negative Bacteria, Hospitals, Risk Assessment |
| Revision History | v2: Add ROR ID. |