BPTF is essential for vaccine-induced germinal center B cell responses [dataset]

Published: 24 June 2026| Version 1 | DOI: 10.17632/x8xyxc8r6v.1
Contributors:
,
,
,
,
,
,
,
,
,
,
,
,
,

Description

This dataset contains the raw data supporting all main and supplementary figures used in the manuscript "BPTF is essential for vaccine-induced germinal center B cell responses," published in Journal of Immunology. The data includes measurements of cellular immune responses in wild-type and transgenic mice following immunization with the mRNA-lipid nanoparticle-based SARS-CoV-2 spike vaccine. It also includes data analyzing the transcriptomic profile of mouse and human B cells responding to vaccination with mRNA-lipid nanoparticle-based SARS-CoV-2 spike vaccine.

Files

Steps to reproduce

Refer to the "Materials and Methods" section of the open access publication.

Institutions

Categories

Immunology, Allergy

Funders

Additional Metadata for Digital Commons Data@Becker

KeywordsGerminal center, Bromodomain PHD finger transcription factor, Vaccination, Cell cycle, Cell death

Related Links

Dataset
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA800176
is related to this dataset
Dataset
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327666
is related to this dataset
Dataset
https://doi.org/10.5281/zenodo.19500486
is related to this dataset
Article
https://doi.org/10.1093/jimmun/vkag126
is related to this dataset

Licence