Dataset for 'MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after WNV infection'

Published: 24 October 2025| Version 1 | DOI: 10.17632/xcwvjzg2hf.1
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Description

This dataset includes raw data for seven main and eight supplementary figures from the manuscript "MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after WNV infection." In this in vivo mouse study, loss of type I IFN signaling reveals that IL-1R/MyD88 pathways in hematopoietic myeloid cells drive WNV pathogenesis, causing gut barrier injury, liver damage, cytokine elevation, and brain inflammation.

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Steps to reproduce

Refer to the "STAR METHODS" section of the publication.

Institutions

  • Washington University in St. Louis
  • Universitatsklinikum Regensburg

Categories

Microbiology, Virology

Funders

Additional Metadata for Digital Commons Data@Becker

KeywordsFlavivirus, West Nile virus, Gastrointestinal tract, Myeloid cells

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