Dataset for "Adolescent girls with type 1 diabetes develop changes in bone prior to evidence of clinical neuropathy"
Description
This dataset contains deidentified information from 33 adolescent girls with (n=21) and without (n=12) type 1 diabetes from 12 to 18 years of age. Parameters in the dataset include general demographics and fracture history, general health information, body composition bone mineral density by DXA, bone microarchitecture and strength by HR-pQCT, blood labs, circulating bone turnover biomarkers, and presence of peripheral neuropathy based on the Michigan Neuropathy Screening Instrument. Full details can be found in the associated files. The collection of this data was conducted with the approval of the Washington University in St. Louis Institutional Review Board (ID# 201908120). Participants provided informed consent for the sharing of de-identified data.
Files are not publicly available
You can contact the author to request the files
Steps to reproduce
Steps to reproduce the data are provided in the "T1D Nerve and Bone Study Methods.pdf" file and "HRpQCT technician notes and protocol.pdf" file.
Institutions
Categories
Funding
National Institute of Diabetes and Digestive and Kidney Diseases
U24DK115255
National Institute of Diabetes and Digestive and Kidney Diseases
T32DK007120
Additional Metadata for Digital Commons Data@Becker
| Keywords | Adolescent, Bone Density, Diabetes Mellitus Type 1, Case-Control Studies, Bone Diseases Metabolic, Bone Remodeling, Diabetic Neuropathies, Osteocalcin, Fractures |