Dataset for 'Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters'

Name: Dataset for 'Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters'
Creator: Nadia Soudani
Published: 2024-08-30T20:05:36.153Z
Keywords: Immunology, Microbiology, Virology, Infectious Disease, Vaccine, Immunity

Soudani, Nadia; Bricker, Traci L.; Darling, Tamarand; Seehra, Kuljeet; Patel, Nita; Guebre-Xabier, Mimi; Smith, Gale; Davis-Gardner, Meredith; Suthar, Mehul S.; Ellebedy, Ali H.; Boon, Adrianus C.M.

doi:10.17632/7my7sszcff.1

Dataset for 'Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters'

Published: 30 August 2024| Version 1 | DOI: 10.17632/7my7sszcff.1

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Description

This dataset contains the raw data supporting all main and supplementary figures used in the manuscript "Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters," published in Journal of Virology (JVI). The data includes measurements of humoral and cellular immune responses in Syrian hamsters following immunization with the nanoparticle recombinant Spike (S) protein-based COVID-19 vaccine (Novavax, Inc.) from different variants. It also includes data comparing the efficacy of the updated monovalent XBB.1.5 variant vaccine to previous COVID-19 vaccines in inducing XBB.1.5 and EG.5.1 neutralizing antibodies and in protecting against a challenge with the EG.5.1 variant of SARS-CoV-2.

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Refer to the "Materials and Methods" section of the publication.